BioMail perform routine searches and gives alerts to users about all new papers in their fields automatically. This program also helps the user to refine search patterns once and for all. All patterns are stored in the database and can be accessed, tuned, or deleted any time. This is also also useful for countries where access to the Internet is not yet widely available. If a person has a permanent e-mail address, but only sporadic www access, she/he only needs to fill out a BioMail form once and then will receive new references from Medline continually.